Searchable abstracts of presentations at key conferences in endocrinology

ea0022p344 | Diabetes | ECE2010

Systemic effect of insulin on local cytokine concentrations in adipose tissue and muscle in healthy humans

Mader Julia K , Ikeoka Dimas , Weinhandl Heinz , Pachler Christoph , Bock Gerlies , Plank Johannes , Ellmerer Martin , Pieber Thomas R

Introduction: Cytokines are produced in different tissues under physiological and pathophysiological conditions. The present study was performed to compare local concentrations of cytokines in subcutaneous adipose tissue and muscle using the open flow microperfusion (OFM) technique, as well as to investigate systemic effects of insulin on interstitial concentrations of these mediators.Methods: Ten healthy volunteers (age: 27±4 years, BMI: 22.6±...